Ohio - Area of significance: Architecture
| Sears, A. B., House |
| Sears, Roebuck and Company |
| Seborn, Frederick Augustus, House |
| Sebring, Frank, House |
| Second Baptist Church |
| Second Hosack House |
| Second Presbyterian Church |
| Second Presbyterian Church |
| Second Street Historic District |
| Secor Hotel |
| Sedamsville River Road Historic District |
| Sedamsville Village Historic District |
| Seeley, Uri, House |
| Seely, Dr. John W., House |
| Seher, William, House |
| Seiberling, Charles Willard, House |
| Seip House |
| Selby Field |
| Selby, Orland, House |
| Selby Shoe Company Building |
| Selle Gear Company |
| Sells, Benjamin, House |
| Sells, Benjamin, Wash House |
| Sells, Eliud, House |
| Seneca Hotel |
| Serquet, Emanuel and Frederick, Farm |
| Sessions House |
| Sessions Village |
| Seville Jail |
| Seymour, William H., House |
| Shaker Farm Historic District |
| Shaker Square |
| Shaker Village Historic District |
| Shambaugh, George, House |
| Shandy Hall |
| Sharon Center Public Square Historic District |
| Sharon Township Town Hall |
| Sharp, Morris, House |
| Sharp-Page House |
| Sharp, Samuel, House |
| Sharp, Stephen, House |
| Shaub, Martin, Mill Site/House |
| Shawen Acres |
| Shaw Farm |
| Shawnee Historic District |
| Shawnee Hotel |
| Shaw, Samuel, Residence |
| Shaw, Sylvester, Residence |
| Shedd-Dunn House |
| Sheets, Andrew, House |
| Sheffield Village Hall |
| Shelby Center Historic District |
| Shelby House |
| Shelby Oakland Mausoleum |
| Sheridan House |
| Sherman, John, Memorial Gateway |
| Sherwood-Davidson And Buckingham Houses |
| Shield's Block |
| Shield's, Edwin M., House |
| Shier, Carl H., House |
| Shiloh Baptist Church |
| Shore High School |
| Short North Historic District |
| Shuey's Mill |
| Shuler & Benninghofen Woolen Mill |
| Shull-Lugenbuhl Farm |
| Sidney Courthouse Square Historic District |
| Sidney Walnut Avenue Historic District |
| Sidney Waterworks And Electric Light Building |
| Sigma Aplpha Epsilon Chapter House of Miami University |
| Sig's General Store |
| Silk City Diner #4655 |
| Simmons, Edwin H., House |
| Simpson, Walter, House |
| Simpson, William A., House |
| Sixth Street Historic District |
| Skeele, Capt. J. S., House |
| Skywood Farms |
| Slingluff, Dr. Joseph, House |
| Sloane, Rush R., House |
| Slocum Hall |
| Smead, David, House |
| Smead House |
| Smith, Benjamin, House |
| Smith, Charles William and Anna, House |
| Smith, David, House |
| Smith-Davis House |
| Smith, Edward, Jr., Farm |
| Smith, Edwin, House |
| Smith-Jessup House |
| Smith, Samuel, House And Tannery |
| Smith, William, House |
| Smith, William R., House |
| Snow, John, House |
| Snow, Russ and Holland, Houses |
| Social Science House |
| Society for Savings Building |
| Soldiers and Sailors Memorial Building and Madison Theater |
| Soldiers' and Sailors' Memorial Chapel |
| Sollars Farmstead |
Data from United States Park Service and Wikidata