North Carolina - Criteria: A (event)
| Deep River Friends Meeting House and Cemetery |
| DeGraffenreidt-Johnson House |
| DeGraffenried Park Historic District |
| Delgrado School |
| Dellinger Mill |
| Dell School Campus |
| Delta Farm |
| Dempsey-Reynolds-Taylor House |
| Depot Historic District |
| Depot Historic District |
| Desserette |
| Devane-MacQueen House |
| Dickinson Avenue Historic District |
| Dilworth Historic District |
| Dismal Swamp Canal |
| Dix Hill |
| Dixon-Leftwich-Murphy House |
| Dockery, Alfred, House |
| Dorland Memorial Presbyterian Church |
| Double Shoals Cotton Mill |
| Downtown Albemarle Historic District |
| Downtown Burlington Historic District |
| Downtown Durham Historic District |
| Downtown Elkin Historic District |
| Downtown Garner Historic District |
| Downtown Gastonia Historic District |
| Downtown Greensboro Historic District |
| Downtown Main Street Historic District |
| Downtown Mocksville Historic District |
| Downtown Mount Holly Historic District |
| Downtown North Historic District |
| Downtown Sanford Historic District |
| Downtown Selma Historic District |
| Downtown Smithfield Historic District |
| Downtown Spruce Pine Historic District |
| Downtown Sylva Historic District |
| Downtown Wake Forest Historic District |
| Downtown Wilkesboro Historic District |
| Druid Hills Historic District |
| DuBois, W. E. B., School |
| Dudley, James Benson, Senior High School and Gymnasium |
| Duke Homestead and Tobacco Factory |
| Duke Memorial United Methodist Church |
| Dula-Horton Cemetery |
| Dunavant Cotton Manufacturing Company |
| Dunn Commercial Historic District |
| Dupree-Moore Farm |
| Durham Cotton Mills Village Historic District |
| Durham Hosiery Mill |
| Durham Hosiery Mill No. 15 |
| Durham Hosiery Mills Dye House |
| Durham Hosiery Mills No. 2-Service Printing Company Building |
| Eagle Lodge |
| East Davis Street Historic District |
| East Durham Historic District |
| East End Historic District |
| East Marion-Belvedere Park Historic District |
| East Raleigh-South Park Historic District |
| East Raleigh Street Historic District |
| East Spencer Graded School |
| East Tennessee & Western North Carolina Railroad Locomotive No. 12 |
| East White Oak School, Former |
| East Wilson Historic District |
| Ebenezer Academy, Bethany Presbyterian Church and Cemetery |
| Ebenezer Methodist Church |
| Ebenezer Presbyterian Church |
| Edenton Cotton Mill Historic District |
| Edenton Historic District |
| Edenton Peanut Factory |
| Edenton Station, United States Fish and Fisheries Commission |
| Edgecombe Agricultural Works |
| Edgewood |
| Edwards Hotel |
| Efird Building |
| Eliada Home |
| Elizabeth City Historic District |
| Elizabeth City State Teachers College Historic District |
| Elizabeth City Water Plant |
| Elizabeth Historic District |
| Elkin Creek Mill |
| Elkland School Gymnasium |
| Elk Park School |
| Ellerbe Springs Hotel |
| Ellington-Ellis Farm |
| Elliott-Carnegie Library |
| Ellis Street Graded School Historic District |
| Ellixson, William, House |
| Elm City Municipal Historic District |
| Elmwood |
| Elmwood |
| Elon College Historic District |
| Emmanuel AME Church |
| EMPIRE GEM (shipwreck and remains) |
| Endor Iron Furnace |
| Enfield Graded School |
| Eno Cotton Mill |
| Ephphatha Church |
| Episcopal Cemetery |
| Erlanger Mill Village Historic District |
| Erwin Commercial Historic District |
Data from United States Park Service and Wikidata
