New York - Significance region: National
| Poughkeepsie Railroad Bridge |
| Pousette-Dart, Richard, House and Studio |
| Priscilla (Long Island Sound Oyster Sloop) |
| Prospect Avenue Subway Station (IRT) |
| Prudential Building |
| Pupin Physics Laboratories, Columbia University |
| Quarters A |
| Quogue Life-Saving Station |
| Radio City Music Hall |
| Rehoboth |
| Rice Hall |
| Riverside Park |
| Roberts Hall |
| Robeson, Paul, Home |
| "Robinson, John Roosevelt ""Jackie"", House" |
| Rockefeller Center |
| Rockefeller, John D., Estate |
| Rockefeller Pocantico Hills Estate Historic District |
| Rockland Print Works |
| Rogers Brothers Farmstead |
| Roosevelt, Eleanor, National Historic Site |
| Roosevelt, Sara Delano, Memorial House |
| Roosevelt, Theodore, Inaugural National Historic Site |
| Root, Elihu, House |
| Rose Hill |
| Round Lake Historic District |
| Royal Blockhouse, The |
| Roycroft Campus |
| Rustin, Bayard, Residence |
| Sagamore Hill National Historic Site |
| Sailors' Snug Harbor National Register District |
| Sanger, Margaret, Clinic |
| Saratoga National Historical Park |
| Saratoga Spa State Park District |
| Schomburg Center for Research in Black Culture |
| Schuyler Flatts |
| Scott, Gen. Winfield, House |
| Seagram Building |
| Seaview Hospital |
| Seneca River Crossing Canals Historic District |
| Seventh Regiment Armory |
| Seward, William H., House |
| Shinnecock Hills Golf Club |
| Simpson Street Subway Station and Substation #18 (IRT) |
| Sinclair, Harry F., House |
| Sixteen Mile District |
| Slabsides (John Burroughs Cabin) |
| Smith, Alfred E., House |
| Smith, Gerrit, Estate |
| Smith, Reuel E., House |
| Soho Historic District |
| Sonnenberg Gardens |
| Sousa, John Philip, House |
| South Street Seaport |
| SPITFIRE (gunboat) |
| St. Ann's Church Complex |
| Stanton, Elizabeth Cady, House |
| Statue of Liberty Enlightening the World |
| Steepletop |
| Stepping Stones (Wilson, Bill and Lois, House) |
| Stewart, A. T., Company Store |
| St. George's Episcopal Church |
| Stickley, Gustav, House |
| Stone Hall |
| Stony Point Battlefield |
| Storrs' Harbor Naval Shipyard Site |
| St. Patrick's Cathedral |
| St. Paul's Chapel |
| St. Paul's Church National Historic Site |
| St. Peter's Church |
| St. Peter's Roman Catholic Church |
| Substation 13 |
| Sunnyside |
| Sunnyside Gardens Historic District |
| Surrogate's Court |
| Sylvester Manor |
| Tenement Building at 97 Orchard Street |
| The Church of the Heavenly Rest and the Chapel of the Beloved Disciple |
| The Frick Collection and Frick Art Reference Library Building |
| Theodore Roosevelt Birthplace National Historic Site |
| The Players |
| Third Judicial District Courthouse |
| Thompson AME Zion Church |
| Tiffany and Company Building |
| Tilden, Samuel J., House |
| Times Square-42nd Street Subway Station |
| Top Cottage |
| Totiakton Site |
| Town Hall |
| Trans World Airlines Flight Center |
| Triangle Shirtwaist Factory |
| Trinity Church and Graveyard |
| Trinity Episcopal Church |
| Troy Savings Bank and Music Hall |
| Tubman, Harriet, Grave |
| Tubman, Harriet, House |
| Tuxedo Park |
| Tweed Courthouse |
| Two Bridges Historic District |
| Union Avenue Historic District |
Data from United States Park Service and Wikidata
