New York - Significance region: National
| Chinatown and Little Italy Historic District |
| Chrysler Building |
| Church of Saint Mary the Virgin and Greeley Grove |
| Church of the Ascension (Protestant Episcopal) |
| Church of the Holy Communion and Buildings |
| Church of the Incarnation and Parish House |
| City Hall |
| City Hall Subway Station (IRT) |
| CLEARWATER (Sloop) |
| Clermont |
| Clinton Avenue Historic District |
| Cobblestone Historic District |
| Coeymans, Ariaanje, House |
| COIMBRA (shipwreck and remains) |
| Cold Spring Harbor Laboratory Historic District |
| Cole, Thomas, House |
| Coltrane House |
| COLUMBIA (steamer) |
| Comstock Hall |
| Concrete-Central Elevator |
| Conference House |
| Conkling, Roscoe, House |
| Control House on 72nd Street |
| Cook, Will Marion, House |
| Cooper Union |
| Copland, Aaron, House |
| Cropsey, Jasper F., House and Studio |
| Croton Aqueduct, Old |
| CULLODEN, H.M.S., Shipwreck Site |
| Cypress Hills National Cemetery |
| Daily News Building |
| Dakota Apartments |
| Delamater, Henry, House |
| Delaware and Hudson Canal |
| Delaware Park-Front Park System |
| Devinne Press Building |
| De Wint House |
| Dorsheimer, William, House |
| Double-Span Whipple Bowstring Truss Bridge |
| Dove, Arthur-Torr, Helen, Cottage |
| Draper, John W., House |
| Duke, James B., Mansion |
| Dunbar Apartments |
| Dunkirk Schooner Site |
| Dutch Reformed Church |
| Dutch Reformed Church |
| Dyckman Street Subway Station (IRT) |
| Dyckman, William, House |
| Eagle Island Camp |
| Earl, Gardner, Memorial Chapel and Crematorium |
| East End Historic District |
| Eastern Parkway |
| Eastman, George, House |
| East Robert Hall |
| Eaton Site |
| EDWARD M. COTTER (fireboat) |
| Elephant Hotel |
| "Ellington, Edward Kennedy ""Duke"", House" |
| Ellis Island |
| Ellsworth, Col. Elmer E., Monument and Grave |
| Elmira College Old Campus |
| Empire State Building |
| English Evangelical Lutheran Church of Dansville |
| Enlarged Erie Canal Historic District (Discontiguous) |
| ENTERPRISE (space shuttle) |
| Equitable Building |
| Erie Canal |
| Eustatia |
| Farmington Quaker Crossroads Historic District |
| Farragut, Admiral David Glasgow, Gravesite |
| Federal Hall National Memorial |
| Federal Office Building |
| Fernow Hall |
| Fifth Avenue-Fulton Street Historic District |
| Fillmore, Millard, House |
| FIREFIGHTER |
| Fire Island Light Station |
| First Houses |
| First National City Bank |
| First Presbyterian Church |
| First Reformed Protestant Dutch Church of Kingston |
| First Shearith Israel Graveyard |
| First Unitarian Church |
| Fish, Hamilton, House |
| Flatiron Building |
| Flint Mine Hill Archeological District |
| Floyd, Gen. William, House |
| Floyd, William, House |
| Forest Park Carousel |
| Fort Crailo |
| Fort Crown Point |
| Fort Greene Historic District |
| Fort Jay |
| Fort Johnson |
| Fort Klock |
| Fort La Presentation Site |
| Fort Massapeag Archeological Site |
| Fort Montgomery Site |
| Fort Ontario |
| Fort Orange Archeological Site |
Data from United States Park Service and Wikidata
