New York - Area of significance: Science
| Albany Academy |
| American Museum of Natural History |
| Barber, Peale's, Farm Mastodon Exhumation Site |
| Bell Telephone Laboratories |
| Bird Homestead |
| Cold Spring Harbor Laboratory Historic District |
| Draper, John W., House |
| Fairchild Mansion |
| Flint Mine Hill Archeological District |
| Founder's Hall, The Rockefeller University |
| General Electric Research Laboratory |
| Hall, James, Office |
| Henson, Matthew, Residence |
| Langmuir, Irving, House |
| Linwood |
| Martin-Fitch House & Asa Fitch, Jr. Laboratory |
| New York Botanical Gardens |
| New York Cancer Hospital |
| Office Building and U.S. Light-House Depot Complex |
| Petrified Sea Gardens |
| Pink House, The |
| Pupin Physics Laboratories, Columbia University |
| Roslyn Cemetery |
| Smith Observatory and Dr. William R. Brooks House |
| Steinheim, Alfred, Museum |
| Strecker Memorial Laboratory |
| Vassar College Observatory |
| Vassar Institute |
| Wardenclyffe Laboratory |
| Willard, Dr. Sylvester, Mansion |
Data from United States Park Service and Wikidata
