New York - Area of significance: Industry
| Scott, R. and W., Ice Company Powerhouse and Ice House Site |
| Searle, Gardner and Company Cuff and Collar Factory |
| Seeley Farmhouse |
| Seneca Falls Village Historic District |
| Shantz Button Factory |
| Sheffield Farms Stable |
| Sheltered Workshop for the Disabled Building |
| Shelter Island Windmill |
| Sibley, Hiram, Homestead |
| Sidney Historic District |
| Simonds, L.C., Adirondack Cabin |
| Sinclair, Harry F., House |
| Sloat House |
| Sloat, Jacob, House |
| Smith, Alexander, Carpet Mills Historic District |
| Smith's, Paul, Electric Light and Power and Railroad Company Complex |
| Snyder Estate Natural Cement Historic District |
| Sohmer and Company Piano Factory |
| Solvay Public Library |
| South Ann Street-Mill Street Historic District |
| South Bay Mill |
| Southfield Furnace Ruin |
| South Otselic Historic District |
| Spear and Company Factory |
| Standard Gage Company Plant |
| Steinway House |
| Sterling Grist Mill Complex |
| Sterlingville Archeological District |
| St. Johnsville Historic District |
| Stone Grist Mill Complex |
| Stone Windmill |
| St. Paul-North Water Streets Historic District |
| Stuyvesant Falls Mill District |
| Syracuse Bread Company Factory |
| Syracuse Lighting Company |
| Taylor Signal Company-General Railway Signal Company |
| Terra Cotta Building |
| The Great Atlantic and Pacific Tea Company Warehouse |
| Ticonderoga Pulp and Paper Company Office |
| Tilley, John S., Ladders Company |
| Tioronda Bridge |
| Titus, Elias, House |
| Torne Brook Farm |
| Tower Homestead and Masonic Temple |
| Triangle Shirtwaist Factory |
| Trico Plant No. 1 |
| Troy Gas Light Company |
| Troy Waste Manufacturing Company Building |
| Ulster and Delaware Railroad Depot and Mill Complex |
| Union Mill Complex |
| United States Lace Curtain Mills |
| United Waste Manufacturing Company Building |
| Utica Daily Press Building |
| Utica Steam and Mohawk Valley Cotton Mill |
| Valley Falls Historic District |
| Valley Paper Mill Chimney and Site |
| Van Rensselaer, Jacob Rutsen, House and Mill Complex |
| Van Wyck-Lefferts Tide Mill |
| Van Zandt, Jacobs and Company Collar and Cuff Factory |
| Victory Mills |
| Village of Antwerp Historic District |
| Village of Greenwich Historic District |
| Visco Meter Factory-Buerk Tool Factory |
| Vosburg Turning Mill Complex |
| Wainscott Windmill |
| Walden, Jacob T., Stone House |
| Wallabout Industrial Historic District |
| Walnut Street Historic District |
| Walsh-Havemeyer House |
| Wappingers Falls Historic District |
| Ward, Caleb T., Mansion |
| Warner, H. H., Building |
| Warrensburg Mills Historic District |
| Waterford Village Historic District |
| Watervliet Arsenal |
| Watkins-Sisson House |
| Welch Factory Building No. 1 |
| West Brothers Knitting Company |
| West Point Foundry |
| West Point Foundry Archeological Site |
| West Stockholm Historic District |
| West Strand Historic District |
| Wheeler, William E., House |
| Whiteside, Barnett and Co. Agricultural Works |
| Wilbur-Campbell-Stephens Company Cuff and Collar Factory |
| Wild, Nathan, House |
| Wild's Mill Complex |
| Wile, M., and Company Factory Building |
| Willard, Dr. Sylvester, Mansion |
| William Barnet & Son Shoddy Mill |
| Williamsville Water Mill Complex |
| William Ulmer Brewery Complex |
| Will, Louis, House |
| Windmill at Water Mill |
| Wing-Northup House |
| W. & L. E. Gurley Building |
| Wollenberg Grain and Seed Elevator |
| Wollensack Optical Company Building |
| Wood and Brooks Company Factory Complex |
| Woodlawn Farm |
Data from United States Park Service and Wikidata
