Missouri - Area of significance: Transportation
| "85th and Manchester ""Three Trails"" Trail Segment" |
| Arrow Rock Ferry Landing |
| Arrow Rock Tavern |
| Barretts Tunnels |
| Bingham-Waggoner House and Estate |
| Blue Mills |
| Bonne Terre Depot |
| Boots Court |
| Burfordville Covered Bridge |
| Caplinger Mills Historic District |
| Carlin-Rathgeber House |
| Cave Spring |
| Chicago and Alton Depot |
| Chicago and Alton Railroad Depot at Higginsville |
| Cobblestone Street |
| Cotton Belt Freight Depot |
| Dauphine Hotel |
| De Hodiamont Car House Historic District |
| Devil's Elbow Historic District |
| Downing Railroad Depot |
| Eads Bridge |
| Fairfax Building, The |
| Firestone Building |
| Fredericktown Missouri Pacific Railroad Depot |
| Frisco Building |
| Green City Railroad Depot |
| Hargrove Pivot Bridge |
| Kansas City Parks and Boulevards Historic District |
| Kansas City Southern Railway Building |
| Kansas City Terminal Railway Company Roundhouse Historic District |
| Kelly's Westport Inn |
| Kirkwood Building |
| Kirkwood Missouri Pacific Depot |
| Lock and Dam No. 20 Historic District |
| Lock and Dam No. 22 Historic District |
| Lock and Dam No. 24 Historic District |
| Lock and Dam No. 25 Historic District |
| Lohman's Landing Building |
| Louisiana Chicago & Alton Railroad Depot |
| Mark Twain Historic District |
| McMurtry Spring and Trail of Tears Roadbed Segment |
| Meramec River U.S. Bridge - J421 |
| Milan Railroad Depot |
| Missouri, Kansas and Texas Railroad Depot |
| Missouri, Kansas, and Texas Railroad Depot |
| Missouri Pacifc Building |
| Missouri Pacific Depot |
| Narrow Gauge Railroad Station |
| Neff Tavern Smokehouse |
| "New Santa Fe ""Three Trails"" Trail Swales" |
| Old Appleton Bridge |
| Olean Railroad Depot |
| Owens-McCoy House |
| Papinville Marais des Cygnes River Bridge |
| Pickwick Hotel, Office Building, Parking Garage and Bus Terminal |
| Pierce Pennant Motor Hotel |
| Pony Express Stables |
| Quincy, Missouri, and Pacific Railroad Station |
| Rail Haven Motel |
| Rivercene |
| Rocheport |
| Rockhill Neighborhood |
| Route 66 Steak 'n Shake |
| Sandy Creek Covered Bridge |
| Santa Fe Trail-Grand Pass Trail Segments |
| Santa Fe Trail-Minor Park, Kansas City, Trail Segments |
| Santa Fe Trail-Saline County Trail Segments |
| Santa Fe Trail-Santa Fe Trail Park, Independence Trail Segments |
| Schlichtig House |
| Schneider, Henry, Building |
| Shamrock Court |
| Sikeston St. Louis, Iron Mountain and Southern Railway Depot |
| St. Charles Historic District |
| St. Louis and San Francisco Railroad Building |
| St. Louis, Iron Mountain and Southern Railroad Depot |
| St. Louis, Iron Mountain and Southern Railroad Depot |
| St. Louis-San Francisco Railroad Depot |
| St. Louis Union Station |
| Studna Garage Building |
| Tower Rock |
| Trail of Tears Roadbed Segment on Josiah Danforth Farm |
| Tuxedo Park Station |
| TWA Administrative Offices Building |
| TWA Corporate Headquarters' Building |
| Union Depot Railroad Co. Building |
| Union Station |
| United Railways Spring Avenue Substation-Trouble Station |
| Upper Bridge |
| Wellston Station |
| Wheaton Missouri and North Arkansas Railroad Depot |
| Wilson's Creek National Battlefield |
| Y Bridge |
Data from United States Park Service and Wikidata
