Missouri - Area of significance: Commerce
| Museum Hill Historic District |
| Mutual Ice Company Building |
| National Bank of Commerce Building |
| National Bank of Rolla Building |
| National Cash Register Company Sales and Repair Building |
| National Cloak and Suit Company |
| Neosho Commercial Historic District |
| Neosho Wholesale Grocery Company |
| Netter-Ullman Building |
| New Franklin Commercial Historic District |
| New Haven Commercial Historic District |
| New Lebanon Historic District |
| Newman Brothers Building |
| "New Santa Fe ""Three Trails"" Trail Swales" |
| Noland, Smallwood V., House |
| North Broadway Glass and Plow Warehouse District |
| North Broadway Wholesale and Warehouse District |
| North Main Street Historic District |
| North Ninth Street Historic District |
| North Riverfront Industrial Historic District |
| Odessa Ice Cream Company Building |
| Oehler Brick Buildings |
| Old City Hall |
| Old New England Building |
| Old Stone Hill Historic District |
| Old Town Historic District |
| Old Webster Historic District |
| Old Webster Historic District |
| Olive and Locust Historic Business District |
| Opera Hall Block |
| Orrville Historic District |
| Owens-McCoy House |
| Ozark Courthouse Square Historic District |
| Palace Clothing Company Building |
| Palace Hotel |
| Palace Hotel |
| Pearl Apartments and Windsor Apartments |
| Peck, George B., Dry Goods Company Building |
| Pennington Drug Company |
| Peters Shoe Company Building |
| Pevely Dairy Company Buildings |
| Pickwick Hotel, Office Building, Parking Garage and Bus Terminal |
| Piney Beach |
| Pitcher Store |
| Plant, Samuel, House |
| Plaza Hotel |
| Plaza Hotel Complex |
| Pleasant Hill Downtown Historic District |
| Poplar Bluff Commercial Historic District |
| President Hotel |
| Producers Ice and Manufacturing Company |
| Professional Building |
| Publicity Building, The |
| Pundt Brothers-Garavaglia Grocery Buildings |
| Quality Hill |
| Quincy, Missouri, and Pacific Railroad Station |
| Rail Haven Motel |
| Railway Exchange Building |
| Ramsey Accessories Manufacturing Corporation |
| Red Cedar Inn |
| Richards and Conover Hardware Company Building |
| Richardson, John D., Dry Goods Company |
| Ridenour-Baker Grocery Company Building |
| Ridgway Apartments |
| Rieger Hotel |
| Riggio Building |
| Rivercene |
| Roberts Chevrolet |
| Robidoux Hill Historic District |
| Robidoux Row |
| Rocheport |
| Rock Fountain Court Historic District |
| Route 66 Steak 'n Shake |
| Royal Tire Service Inc. Building |
| Russell Hotel |
| Ryan Block |
| Safeway Stores and Office and Warehouse Building |
| Sanitol Building |
| Sanning, P.A., Store |
| Santa Fe Trail-Grand Pass Trail Segments |
| Santa Fe Trail-Minor Park, Kansas City, Trail Segments |
| Santa Fe Trail-Saline County Trail Segments |
| Santa Fe Trail-Santa Fe Trail Park, Independence Trail Segments |
| Sappington, William B., House |
| Sarcoxie Public Square Historic District |
| Savoy Hotel and Grill |
| Schneider, Henry, Building |
| Schnier, Fred, Building |
| Schowengerdt, Ernst, House |
| Scotia Iron Furnace Stack |
| Scruggs-Vandervoort-Barney Warehouse |
| Scudder Motor Truck Company Building |
| Sears, Roebuck and Company Warehouse Building |
| Sedalia Commercial Historic District |
| Selkirk, Ben J. and Sons, Building |
| Seven Gables Building |
| Seven-Up Company Headquarters |
| Shamrock Court |
| Shell Building, The |
| Silk Exchange Building |
Data from United States Park Service and Wikidata
