Mississippi - Significance region: Local
| Walker-Critz House |
| Walker High School |
| Walker, H.S. and Mattie M., House |
| Walnut Hills |
| Walthall County Courthouse and Jail |
| Ward House |
| Ward, Junius R., House |
| Warren-Erwin House |
| Warren-Guild-Simmons House |
| Washington Avenue-Main Street Historic District |
| Washington County Courthouse |
| Washington Methodist Church |
| Washington Street Historic District |
| Waterhouse-Simmons House |
| Water Valley Main Street Historic District |
| Waterways Experiment Station |
| Watkins, W. W., House |
| Waveland Elementary School |
| Webb, George, House |
| Webb School/Gulf Coast Community Action Agency |
| Wechsler School |
| Weinberg House |
| Weir, Col. John, House |
| Well, The |
| Wesley Memorial Methodist Episcopal |
| Wesley Methodist Church Historic District |
| Wesson Presbyterian Church |
| West Beach Historic District |
| Westbrook Cotton Gin |
| West Capitol Street Historic District |
| West Central Historic District |
| West Commerce Street Historic District |
| West Historic District |
| Westphal, Laura, House |
| West Point Central City Historic District |
| West Point School Historic District |
| West Point Unified Historic District |
| Wetherbee House |
| White-Alford House |
| White Cottage |
| Whitehead and Lloyd Motor Company |
| Wiener, Dr. Julian and Kathryn, House |
| Wiener House at 228 Ridge Drive |
| Wildwood Plantation Commissary and Shop |
| Wilkes, Stephen H., House |
| Wilkinson, Winston, House |
| William and Mary McGee House |
| Williams, Alex, House |
| Williams, Jim, House |
| Williams Landing and Eastern Downtown Residential Historic District |
| Willing, Col. William James, House |
| Wilson House |
| Winchester House |
| Winona Commercial Historic District |
| Winona Community House |
| Winona Historic District |
| Wisteria Hotel |
| Wolfe House |
| Wood Home for Boys |
| Woodland Plantation |
| Woodlawn Historic District |
| Woodstock |
| Woodville Historic District |
| Woolwine, J.W., Homes |
| Woolworth Building |
| Wright House |
| Wyatt, W. W., House |
| Yates-Flora House |
| Yazoo and Mississippi Valley Passenger Depot |
| Yazoo & Mississippi Valley Railroad Depot |
| Yokena Presbyterian Church |
| Young-Bradfield House |
| Young, George Wright, House |
| Young House |
| Zion Baptist Church |
Data from United States Park Service and Wikidata