Mississippi - Role: Building
| Riverside Plantation |
| Robbins House |
| Robertson, Smith, Elementary School |
| Robertson-Yates House |
| Rodney Presbyterian Church |
| Rogers, Emma and Ed, House |
| Rogers, Francis M., House |
| Rogers House |
| Rogers, Newell, House |
| Roos House |
| Rosalie |
| Rose, Adolph, Building |
| Rosedale |
| Rosedale Plantation |
| Rose Hill Missionary Baptist Church |
| Rosemary-Humphreys House |
| Rosemont |
| Rosswood |
| Routhland |
| Ruleville Depot |
| Sacred Heart Roman Catholic Church |
| Sadler House |
| Saenger Theater |
| Saenger Theatre |
| Saint John's Episcopal Church |
| Saint Mark's Episcopal Church |
| Salem School, Old |
| Salisbury Plantation |
| Sand Spring Presbyterian Church |
| Saragossa |
| Saunders-Paine House, The |
| Scales, William Henry, House |
| Scherck, R. T., House |
| Scherer House |
| Seashore Campground School |
| Second Street Historic District |
| Sedgewood Plantation |
| Selma Plantation House |
| Shadyside |
| Shaw Consolidated School |
| Shaw Homestead |
| Shaw-Nosser House |
| Shelton House |
| Sherman Line Rosenwald School |
| Shlenker House |
| Short's Hill |
| Shrock House |
| Shubuta Baptist Church |
| Shubuta Methodist Episcopal Church, South |
| Sillers, Walter, Sr., House |
| Simmons Farmhouse |
| Simmons House |
| Simmons House |
| Simmons & Wright Company, The |
| Simpson County Courthouse |
| Sims-Brown House |
| Sims House |
| Smart-Griffin House |
| Smith, A. L., House |
| Smith Apartments |
| Smith-Buntura-Evans House |
| Smith, Charles F., House |
| Smithland |
| Smith-McClain-Buckley House |
| Smyth, Benjamin Franklin, House |
| Snowdoun |
| South Vicksburg Public School No. 200 |
| Southworth House |
| Spain House |
| Spann, Pearl, Elementary School |
| Spengler's Corner |
| Spengler-Thomas Building |
| Spight, F. L., House |
| Spinks Plantation |
| Springfield Plantation |
| Spring Hill Missionary Baptist Church |
| Stafford's Wells Hotel |
| Stamp’s Super Burgers |
| Standard Drug Company |
| Stanton Hall |
| Steele, L. C., House |
| Stephenson-Allen House |
| Stevens-Buchanan House |
| Stevenson Primary School |
| Stewart-Anderson House |
| St. Francis Xavier Convent |
| St. Mary's By the River |
| St. Matthew Evangelical Lutheran Church |
| Stogner House |
| Stone, John M., Cotton Mill |
| Stone-Reid House |
| Storer House |
| St. Patrick Catholic Church |
| St. Paul's Episcopal Church Rectory, Old |
| St. Peter's Episcopal Church |
| Strawberry Patch-McKay House |
| Stringer House |
| Sub Rosa |
| Summer Trees |
| Sumrall-Albritton House |
Data from United States Park Service and Wikidata
