Michigan - Significance region: National
| Acres, The |
| Affleck, Gregor S. and Elizabeth B., House |
| ALGOMA |
| All Saints' Episcopal Church |
| Alten, Mathias., House and Studio |
| AMERICA |
| American Seating Company Factory Complex |
| Ann Arbor Central Fire Station |
| Applewood |
| Au Sable Light Station |
| BARNEY, F. T., Shipwreck |
| Battle Creek Sanitarium |
| Bay View |
| Botsford-Graser House |
| Bugai Site (20SA215) |
| Calumet Historic District |
| CHESTER A. CONGDON |
| CITY OF MILWAUKEE |
| Cliffs Shaft Mine |
| Commandant's Quarters |
| Cooke Hydroelectric Plant |
| Cranbrook |
| Croton Dam Mound Group |
| Croton Hydroelectric Plant |
| CUMBERLAND |
| Curwood Castle |
| Dearborn Inn and Colonial Homes |
| De Pree, Max and Esther, House |
| Detroit Cornice and Slate Company Building |
| Detroit Industry Murals, Detroit Institute of Arts |
| Detroit Masonic Temple |
| Detroit Observatory |
| Detroit Zoological Park |
| Douglas, James and Jean, House |
| Dow, Alden B., House and Studio |
| Dow, Herbert H., House |
| Dry Dock Engine Works-Detroit Dry Dock Company Complex |
| Dunbar Hospital |
| Durant-Dort Carriage Company Office |
| Eagle Harbor Schoolhouse |
| Eagle River Historic District |
| Elmwood |
| EMPEROR |
| Eustace Hall |
| Fair Lane |
| Fayette |
| First Methodist Episcopal Church of Pokagon |
| Fisher and New Center Buildings |
| Fisher Building |
| Fletcher Site |
| Ford, Edsel and Eleanor, House (Gaukler Pointe) |
| Ford Piquette Avenue Plant |
| Ford, President Gerald R., Jr., Boyhood Home |
| Ford River Rouge Complex |
| Fort Gratiot |
| Fort Mackinac |
| Fort Michilimackinac |
| Fort St. Joseph Site |
| Fort Wayne |
| Fort Wilkins |
| Fox Theater Building |
| Francis Metallic Surfboat |
| Freer, Charles Lang, House |
| Garden Island Indian Cemetery |
| General Motors Building |
| General Motors Research Laboratory |
| General Motors Technical Center |
| General Motors Technical Center |
| GEORGE M. COX |
| GLENLYON |
| Goetsch-Winckler House |
| Gordon Hall |
| Grand Hotel |
| Grand Trunk Western Railroad Depot |
| Granot Loma |
| Greenfield Village and Henry Ford Museum |
| Gros Cap Archaeological District |
| Guardian Building |
| Gwinn Model Town Historic District |
| Hamtramck Stadium |
| Hanka, Herman and Anna, Farm |
| Hemingway, Ernest, Cottage |
| HENNEPIN Self-unloading Steamship (Shipwreck) |
| HENRY CHISHOLM |
| Highland Park Plant, Ford Motor Company |
| Holcombe Site |
| Horton Bay General Store |
| Hull's Trace North Huron River Corduroy Segment |
| HURON (lightship) |
| Indian Dormitory |
| Jackson Mine |
| Kahn, Albert, House |
| KAMLOOPS |
| Kellogg, W.K., House |
| Kresge, S. S., World Headquarters |
| Ladies' Literary Club |
| Lardner, Ring, House |
| Laurium Historic District |
| Mackinac Island |
| Makinen, John J., Bottle House |
Data from United States Park Service and Wikidata
