Michigan - Significance region: Local
| Dober Mining Company House |
| Dodge Mansion |
| Doll, Benedict, House |
| Doughty House |
| Douglas House |
| Douglass House |
| Downtown Adrian Commercial Historic District |
| Downtown Allegan Historic District |
| Downtown Holly Commercial District |
| Downtown Lowell Historic District |
| Downtown Three Rivers Commercial Historic District |
| Drake, Benjamin and Maria (Ogden), Farm |
| Duff Building |
| Dundee Historic District |
| Durand High School |
| Dutton, James B., House |
| Dwight, Austin H., and Frankie A., Summer House |
| Eagle Theater |
| Earl, Thomas, House |
| East Chicago Street Historic District |
| East Elm-North Macomb Street Historic District |
| Eastern Avenue School |
| Eastern Market Historic District |
| Eastern Michigan University Historic District |
| East Ferry Avenue Historic District |
| East Genesee Historic Business District |
| East Grand Boulevard Historic District |
| East Hancock Neighborhood Historic District |
| East Jordan Lumber Company Store Building |
| East Ludington Avenue Historic District |
| East Michigan Avenue Historic District |
| East Mitchell Street Historic District |
| East River Road Historic District |
| East River Road-North Hickory Canal Bridge |
| East Saginaw Historic Business District |
| East Ward School |
| Eaton County Courthouse |
| Eberts, John and Emma Lacey, House |
| Eddystone Hotel |
| Eden Springs Park |
| Edson, Moore and Company Building |
| Edwards, Rock S., Farmstead |
| Eesley, J. F., Milling Co. Flour Mill-Elevator |
| Eggleston School |
| Eighth Precinct Police Station |
| Elk Rapids First Methodist Episcopal Church |
| Elk Rapids Township Hall |
| Elks Lodge Building |
| Elks Temple Building |
| Elm Lawn Cemetery |
| El Tovar Apartments |
| Elwood Bar |
| Empire School |
| Emporium |
| Endicott, John & Mary Elizabeth Booth, House |
| Engine House No. 11 |
| Engine House No. 18 |
| Ericson, Rudolf, House |
| Erin-Warren Fractional District No. 2 Schoolhouse |
| Escanaba Central Historic District |
| Everitt, Orson, House |
| Everts, Caleb, House |
| Fairgrove Avenue Historic District |
| Fairman Building |
| Fairweather, James F.-Lamb, Jacob C., House |
| Fallasburg Historic District |
| Falls Location Historic District |
| Fanckboner-Nichols Farmstead |
| Farmington Historic District |
| Farwell Building |
| Faunce-McMichael Farm |
| Fead, John L., House |
| Federal Building |
| Federal Building |
| Felt, Dorr E., Mansion |
| Fenton Railroad Depot |
| Ferry, Edward P., House |
| Ferry Street Historic District |
| Ferry Stree-Thorofare Canal Bridge |
| Ferry, William Hawkins, House |
| Fidelity Building |
| Fine Arts Building |
| Finnish and Swedish Mercantile Association Building |
| First Baptist Church |
| First Baptist Church of Detroit |
| First Baptist Church of Grand Blanc |
| First Congregational Church |
| First Congregational Church |
| First Congregational Church |
| First Congregational Church |
| First Congregational Church |
| First Federal Building |
| First Methodist Episcopal Church |
| First Methodist Episcopal Church of Farmington |
| First National Bank and Trust Company Building |
| First National Bank Building |
| First National Bank Building |
| First (Park) Congregational Church |
| First Presbyterian Church |
| First Presbyterian Church |
Data from United States Park Service and Wikidata
