Michigan - Area of significance: Industry
| Rock Harbor Lighthouse |
| Romeo Historic District |
| Royce, Steven, House |
| Sage Library |
| Saginaw Central City Historic Residential District |
| Saginaw City Historic Business District |
| Schoolcraft Furnace Site |
| Schuyler Mill-Ford Soybean Plant Complex |
| Shay Complex |
| Shay Locomotive |
| Shelden Avenue Historic District |
| Shelden, Ransom B., House |
| Shields, Patrick and Sarah Dobbins, House |
| Sligh Furniture Company Building |
| Smith-Culhane House |
| Smith-Dengler House |
| Smith, Samuel L., House |
| South Michigan Avenue Historic District |
| South Street Historic District |
| Spies Boardinghouse |
| S.S. VALLEY CAMP |
| Stafford, Frederick H. and Elizabeth, House |
| Stafford House |
| Stafford, W. R., Planing Mill Site |
| Stafford, W. R., Saw Mill Site |
| Stearns, Frederick, Building |
| St. Mary's Falls Canal |
| Stuart Area Historic District |
| Temple, Samuel W., House |
| Tinker, Harry C., House |
| Tuttle, Columbus, House |
| Upper Peninsula Brewing Company Building |
| VanderHeyden, William H., House |
| Van Platen-Fox Lumber Camp Historic Complex |
| Vermont House and Fenton Grain Elevator |
| Virginia Park Historic District |
| Wall-Seppanen House |
| Warren Featherbone Company Office Building |
| Warren Motor Car Company Building |
| Watervale Historic District |
| Weis Manufacturing Company |
| West Bridge Street Historic District |
| Western Knitting Mills |
| West Pearl Street Historic District |
| West Saint Clair Street Historic District |
| West Side Historic Residential District |
| West Town Historic Commercial and Industrial District |
| Williams, Alfred, House |
| Williams, Benjamin, House |
| Wilson Barn |
| Wisconsin Land and Lumber Company Office Building |
| Wolcott Mill |
| Woodard, Lee, and Sons Building |
| Woodard, Lyman, Company Workers' Housing |
| Woodard, Lyman, Furniture and Casket Company Building |
| Wright, Ammi and William, House |
| Ypsilanti Historic District |
| Zinc Collar Pad Company Building |
Data from United States Park Service and Wikidata