Massachusetts - Significance region: National
| Craigville Historic District |
| Crane and Company Old Stone Mill Rag Room |
| Crane, Thomas, Public Library |
| Crocker, Capt. Alexander, House |
| Crocker, Ebenezer, Jr., House |
| Crowell-Smith House |
| Crowninshield House |
| Cuffe, Paul, Farm |
| Cushing, Caleb, House |
| Custom House District |
| Cypress-Emerson Historic District |
| Daly, Reginald A., House |
| "Daniel Chester French Home and Studio, ""Chesterwood""" |
| Davis, Isaac, Trail |
| Davis, Robert S., House |
| Davis, Thomas Aspinwall, House |
| Davis, William Morris, House |
| Day, Josiah, House |
| Derby Summerhouse |
| Derby Waterfront District |
| Dickinson, Emily, House |
| Dill Building |
| Dimock Community Health Center Complex |
| Dorchester Heights National Historic Site |
| Douglass, Alfred, House |
| Downtown Lawrence Historic District |
| Du Bois, William E.B., Boyhood Homesite |
| Dune Shacks of Peaked Hill Bars Historic District |
| Dutch House, The |
| Duxbury Pier Light |
| East End Historic District |
| Elliot, Gen. Simon, House |
| Elmwood |
| Emerson, Ralph Waldo, House |
| Emmett Cottage |
| ERNESTINA (schooner) |
| Essex Company Machine Shop |
| Essex Insitiute Historic District |
| Ether Dome, Massachusetts General Hospital |
| Fairbanks House |
| Faneuil Hall |
| Federal Square Historic District |
| Fenway Park |
| Fenway Studios |
| Fernald, Walter E., State School |
| Fernwood |
| Fessenden, Reginald A., House |
| Fire Station No. 7 |
| First Baptist Church |
| First Church of Christ, Lancaster |
| Fisher Hill Historic District |
| Flying Horses |
| Fort Banks Mortar Battery |
| Fort Independence |
| Fort Pickering |
| Fort Sewall |
| Fort Warren |
| Fowle, Edmund, House |
| Foxborough State Hospital |
| Framingham Railroad Station |
| Francis, Dr. Tappan Eustis, House |
| FRANK A. PALMER AND LOUIS B. CRARY (Shipwreck) |
| Frelinghuysen Morris House and Studio |
| French Cable Hut |
| Fruitlands |
| Fuller House |
| Fuller, Margaret, House |
| Fuller, Peter, Building |
| Gardner, Isabella Stewart, Museum |
| Gardner-Pingree House |
| Garrison, William Lloyd, House |
| Gay Head-Aquinnah Town Center Historic District |
| Gedney and Cox Houses |
| Gerry, Elbridge, House |
| Gifford Farm |
| Glover, Gen. John, House |
| Goddard, John, House |
| Goddard Rocket Launching Site |
| Goodale Homestead |
| Goodspeed House |
| Goodwood |
| Gore Place |
| Gough, John B., House |
| Grace Episcopal Church |
| Graffam Development Historic District |
| Grange, The |
| Grant, Benjamin, House |
| Gray, Asa, House |
| Gray, Capt. Thomas, House |
| Great Blue Hill Weather Observatory |
| Green Hill Historic District |
| Hale, Edward Everett, House |
| Hamilton Hall |
| Hampden County Courthouse |
| Hancock Cemetery |
| Hancock-Clarke House |
| Hancock Shaker Village |
| Harding, Chester, House |
| Harris, John, House and Farm |
| Harvard Stadium |
Data from United States Park Service and Wikidata
