Massachusetts - Significance region: Local
| Dunbar-Vinton House |
| Dunstable Center Historic District |
| Dunstable Town Hall |
| Duprey Building |
| Durant, Capt. Edward, House |
| Durfee, B.M.C., High School |
| Durfee, Henry E., Farmhouse |
| Durgin, E. A., House |
| Durgin House |
| Dutton-Holden Homestead |
| Dwight-Derby House |
| Dwight, Edmund, House |
| Dwight-Henderson House |
| Dwight Manufacturing Company Housing District |
| Dworman, David, Three-Decker |
| Eagle Hill Historic District |
| Eagleville Historic District |
| Eames, Philip, House |
| East Attleborough Academy |
| East Blackstone Friends Meetinghouse |
| East Blackstone Village Historic District |
| East Boston High School, Old |
| East Bridgewater Common Historic District |
| East Cambridge Historic District |
| East Charlemont District School |
| East End Historic District |
| Eastern Middlesex County Second District Court |
| East Freetown Historic District |
| East Gloucester Square Historic District |
| Eastham Center Historic District |
| East Hawley Center Historic District |
| East Holliston Historic District |
| East Lawn Cemetery and Sherman Burbank Memorial Chapel |
| East Leverett Historic District |
| East Main-High Street Historic District |
| East Main Street Cemetery |
| East Main Street-Cherry Street Historic District |
| East Main Street Historic District |
| East Otis Schoolhouse |
| East Parish Burying Ground |
| East Parish Meeting House |
| East Princeton Village Historic District |
| East Rochester Church and Cemetery Historic District |
| East Taunton Fire Station |
| East Village Historic District |
| Eastwood Cemetery |
| Eaton, Crane & Pike Company Factory |
| Eaton-Moulton Mill |
| Eaton-Prescott House |
| Eddy Block |
| Eddy, George W., House |
| Edward's Plain-Dowse's Corner Historic District |
| Egleston Substation |
| Elder, Samuel, House |
| Eldredge Public Library |
| Eldridge House |
| Elias Brookings School |
| Eliot Congregational Church |
| Eliot Hall |
| Elks Building |
| Ellice School |
| Elliott, Luther, House |
| Ellis, Asa, House |
| Ellis, Moses, House |
| Elm Bank |
| Elm Cottage/Blanding Farm |
| Elm Hill Avenue-Georgia Street-Cheney Street Historic District |
| Elm Hill Farm Historic District |
| Elm Hill Park Historic District |
| Elm-Maple-South Streets Historic District |
| Elm Park and Isaac Sprague Memorial Tower |
| Elm Street Fire House |
| Elm Street Fire Station |
| Elm Street Historic District |
| Elm Street Historic District |
| Emerson, Capt. Oliver, Homestead |
| Emerson-Franklin Poole House |
| Emerson House |
| Emerson Shoe Company |
| Emmons, G.B., House |
| Endicott Estate |
| Engine House No. 34 |
| Engine House No. 6 |
| English High School |
| Erikson, Knut, Three-Decker |
| Esmond Street Historic District |
| Essex Company Offices and Yard |
| Essex County Court Buildings |
| Essex Street Historic District |
| Essex Town Hall and TOHP Burnham Library |
| Estey Tavern |
| Ethel Apartment House |
| Euclid Avenue-Montrose Street Historic District |
| Eustis Estate Historic District |
| Evangelical Free Church |
| Evans Court Apartment Building |
| Everett Avenue-Sheffield Road Historic District |
| Evergreen Cemetery |
| Evergreen Cemetery |
| Exchange Hall |
Data from United States Park Service and Wikidata
