Massachusetts - Significance region: Local
| Staples, Sylvanus N., House |
| Stark Building |
| Stark, Robert M., House |
| State Armory |
| St. Charles Borromeo Church |
| Stearns, Amos, House |
| Stearns Building |
| Stearns, R. H., House |
| Steele, John, House |
| Sterling Center Historic District |
| Sterling, Ella Mahalla Cutter, House |
| Stetson-Ford House |
| Stetson Hall |
| Stetson House |
| Stevens, Abiel, House |
| Stewart, Frank H., House |
| Stewart, Henry, House |
| St. George Antiochian Orthodox Church |
| St. George's Greek Orthodox Church |
| Still River Baptist Church |
| Stimpson, William, House |
| St. James Apartments, The |
| St. James Episcopal Church |
| St. John's Roman Catholic Church |
| St. Joseph's Church |
| St. Joseph's Convent and School |
| St. Joseph's Roman Catholic Church Complex |
| St. Joseph's School |
| St. Joseph's School |
| St. Luke's and St. Margaret's Church |
| St. Mark's Methodist Church |
| St. Mary's Catholic Church |
| St. Mary's Church and Cemetery |
| St. Mary's Complex |
| St. Mary's Episcopal Church |
| St. Mary's Roman Catholic Church Complex |
| St. Michael's Church |
| St. Nicholas Orthodox Church and Rectory |
| Stockbridge Casino |
| Stoliker, Edna, Three-Decker |
| Stone Building |
| Stone, Edward, Three-Decker |
| Stoneham Firestation |
| Stoneham Public Library |
| Stoneholm |
| Stone House |
| Stone, Joseph, House |
| Stone, Lorenzo R., House |
| Stone's Bridge |
| Stony Brook-Factory Village Historic District |
| Stony Farm |
| Story Grammar School |
| St. Patrick's Church |
| St. Paul's Parish Church |
| St. Peter's Roman Catholic Church-St. Mary's School |
| Stratton, Edward B., House |
| Strong House |
| St. Stephen's Memorial Church |
| St. Thomas Epsicopal Church |
| Students House |
| Sudbury Center Historic District |
| Sullivan, Edward, House |
| Sullivan's Corner Historic District |
| Summer Street Historic District |
| Sumner, George, House |
| Sumner Hill Historic District |
| Sunderland Center Historic District |
| Sutton Block |
| Sutton Center Historic District |
| Swadkins, Thomas, House |
| Swampscott Cemetery |
| Swampscott Railroad Depot |
| Swan, Asie, House |
| Swan, Henry, House |
| Swansea Friends Meetinghouse and Cemetery |
| Swansea Village Historic District |
| Swasey, James, House |
| Sweet, Albert, House |
| Sweetser, Daniel, House |
| Sweetser, Michael, House |
| Sweetser, Warren, House |
| Swetland-Pease House |
| Sykes House |
| Symmes, Deacon John, House |
| Symmes, Marshall, House |
| Symmes, Marshall, Tenant House |
| Symmes, Stephen, Jr., House |
| Symonds, Thomas, House |
| Tack Factory, The |
| Taconic and West Avenues Historic District |
| Tapin, Eugene, House |
| Tarklin School |
| Tashmoo Springs Pumping Station |
| Taunton Alms House |
| Taunton Green Historic District |
| Taunton Public Library |
| Tavern Acres Historic District |
| Tavern Farm, Old |
| Tay, Jesse, House |
| Taylor-Bray Farm |
Data from United States Park Service and Wikidata
