Massachusetts - Area of significance: Science
| Arnold Arboretum |
| Birkhoff, George D., House |
| Borderland Historic District |
| Bowditch, Nathaniel, House |
| Bridgman, Percy, House |
| Cloverden |
| Daly, Reginald A., House |
| Davis, William Morris, House |
| ERNESTINA (schooner) |
| Ether Dome, Massachusetts General Hospital |
| Fessenden, Reginald A., House |
| Goddard Rocket Launching Site |
| Gray, Asa, House |
| Great Blue Hill Weather Observatory |
| Hammond Castle |
| Lincoln Historic District |
| Little, Arthur D., Inc., Building |
| Lovering, Joseph, House |
| Marconi Wireless Station Site |
| Mason, W. A., House |
| Massachusetts General Hospital |
| Minot, George R., House |
| Murphy, William, House |
| Norwood-Hyatt House |
| Pill Hill Historic District |
| Richards, Ellen H. Swallow, House |
| Richards, Theodore W., House |
| Rumford, Count, Birthplace |
| Thomson, Elihu, House |
| University Museum |
| Warelands |
Data from United States Park Service and Wikidata
