Maine - Significance region: National
| Agassiz Bedrock Outcrop |
| AMERICAN EAGLE (schooner) |
| Archeological Site No. 39.1 |
| Arnold Trail to Quebec |
| Bailey Island Cobwork Bridge |
| Battery Steele |
| Best, Charles, House |
| Blaine, James G., House |
| BOWDOIN (schooner) |
| Brick House Historic District |
| Calais Observatory |
| Camden Amphitheatre and Public Library |
| Camp Hammond |
| Cobbosseecontee Dam Site |
| Cushnoc (ME 021.02) |
| Day, Holman, House |
| Dow, Gen. Neal, House |
| Eagle Island |
| Eegonos |
| Federal Street Historic District |
| Flagg, James Montgomery, House |
| Fort George |
| Fort Halifax |
| Fort Kent |
| Fort Knox State Park |
| Fort McClary |
| Fort O'Brien |
| Fort Popham Memorial |
| Fort Western |
| Frye, Sen. William P., House |
| Fuller-Weston House |
| Gehring Clinic |
| Gilman, Daniel Coit, Summer Home |
| Goddard Site |
| Governor's House |
| GRACE BAILEY (two-masted schooner) |
| Graves, Abbott, House |
| Hamilton, Jonathan, House |
| Hamlin, Hannibal, House |
| Harpswell Meetinghouse |
| Hawthorne, Nathaniel, Boyhood Home |
| Haystack Mountain School of Crafts |
| Hinckley Good Will Home Historic District |
| Homer, Winslow, Studio |
| Howels, William Dean, House |
| ISAAC H. EVANS (schooner) |
| J. & E. RIGGIN (schooner) |
| Jewett, Sarah Orne, House |
| Jones, Abel, House |
| Jones, Eli and Sybil, House |
| Kent, Rockwell, Cottage and Studio |
| King, Thomas, Inscription |
| Lady Pepperrell House |
| Leighton, Adam P., House |
| LEWIS R. FRENCH (schooner) |
| Libby Island Light Station |
| Lightship No. 112, NANTUCKET |
| Lion, The (locomotive) |
| Lombard, Alvin O., House |
| Maine Archeological Survey site 62.46 |
| May, Sophie, House |
| McCurdy Smokehouse |
| McIntire Garrison House |
| McLellan-Sweat Mansion |
| MERCANTILE (schooner) |
| Merrill-Poor House |
| Morse-Libby Mansion |
| Mount Desert Island Hiking Trail System |
| Munsungan-Chase Lake Thoroughfare Archeological District |
| Nazi Spy Landing Site |
| Nickels-Sortwell House |
| Norridgewock Archeological District |
| Ocean Park Historic Buildings |
| Ogunquit Playhouse |
| Old York Gaol |
| Olmsted, Frederick Law, Summer Home |
| Olson House |
| Parsons, Josiah K., Homestead |
| Parsons, Marion, House |
| Pemaquid Restoration and Museum |
| Pendle Hill |
| Penobscot Expedition Site |
| Penobscot Salmon Club and Pool |
| Pentagoet Archeological District |
| Poland Spring Bottling Plant and Spring House |
| Pond Meeting House |
| Popham Colony Site |
| Portland Observatory |
| Portsmouth Naval Shipyard |
| Privateer Brigantine DEFENCE Shipwreck Site |
| Redwood |
| Reed, Thomas Brackett, House |
| Robinson, Edward Arlington, House |
| Rockport Historic Kiln Area |
| Russwurm, John B., House |
| Schoodic Peninsula Historic District |
| Sebasticook Lake Fishweir Complex |
| Sebec-Piscataquis River Confluence Prehistoric Archeological District |
| Seguin Island Light Station |
| Shaker Village |
Data from United States Park Service and Wikidata
