Iowa - Role: Building
| Scheibe, Julius, Cottage |
| Schindhelm-Drews House |
| Schlapp, George E., House |
| Schmidt Block |
| Schmidt, F. Jacob, House |
| Schmidt House |
| Schmidt, Louis C. and Amelia L., House |
| Schmitt and Henry Manufacturing Company |
| Schnellbacher, John and Fredericka Meyer, House |
| Schoenenberger, Nicholas, House and Barn |
| Scholte, Dominie Henry P., House |
| School Number 6 |
| Schramm Building |
| Schricker, John C., House |
| Schricker, John, House |
| Schroeder Bros, Meat Market |
| Schroeder-Klein Grocery Company Warehouse |
| Schulein, Ben and Harriet, House |
| Schultz Brothers Drug Store |
| Science Hall |
| Sciola Missionary Baptist Church |
| Scott County Jail |
| Scottish Rite Consistory Building |
| Scott, Mary A. and Caleb D., House |
| Seaman, Roy C. and Lena (Johnson), House |
| Second Baptist Church |
| Second Baptist Church |
| Secrest Octagon Barn |
| Security Building |
| Security Building |
| Seeberger-Loring-Kilburn House |
| Seerley, William and Mary (Messersmith) Barn and Milkhouse-Smokehouse |
| Seminole Valley Farmstead |
| Seney, Charles, House |
| Sentinel Block |
| Seth Richards Commercial Block |
| Seven Oaks |
| Severson, Nels, Barn |
| Sexton Hotel |
| Shantz, Martin L. and Mary Jane (Yount), House |
| Sharon, Fred B., House |
| Sharon Methodist Episcopal Church |
| Shaw, Col. William T. and Elizabeth C., House |
| Shaw, E. A., House |
| Shay, Lee, Farmhouse |
| Sheaffer, Craig and Virginia, House |
| Sheaffer, Walter A., House |
| Shea, John J. and Agnes, House |
| Shelby Consolidated School |
| Shelby County Courthouse |
| Sheldahl First Norwegian Evangelical Lutheran Church |
| Shellito, Dr. Judd C. and Margaret S. Clarke, House |
| Sherman, Hoyt, Place |
| Sherman, Lampson P., House |
| Sherrill Mount House |
| Shields Woolen Mill |
| Shimek, Bohumil, House |
| Shipley, C. P., House |
| Shoemake, John H., House |
| Shores-Mueller Company |
| Shriver, William R. and Martha Foster, House |
| Siebels' Department Store-Boyer Valley Bank |
| Sieben, Mrs. Margaret, House |
| Siemer House |
| Sigma Pi Fraternity House |
| Sigma Sigma-Delta Chi Fraternity House |
| Sigourney Public Library |
| Simmons Hardware Company Warehouse |
| Simmons, John P., House |
| Simpson, Charles S., House |
| Sinclair Building-Smulekoffs Furniture Store |
| Sinclair, Caroline, Mansion |
| Singmaster, C.F. and Mary, House |
| Sinnett Octagon House |
| Sioux City Baptist Church |
| Sioux City Central High School |
| Sioux City Fire Station Number 3 |
| Sioux City Free Public Library |
| Sioux City Linseed Oil Works |
| Sioux City Masonic Temple |
| Sioux City Public Library-North Side Branch |
| Sioux City Public Library (Smith Villa Branch) |
| Sioux County Courthouse |
| Sioux Theatre |
| Sitz, Rudolph H., Building |
| Slayton Farms-Round Barn |
| Slye, Thomas, House |
| Smith, Alvord I., House |
| Smith Farmhouse |
| Smith, Gen. Cass and Belle, House |
| Smith, Henry H./J.H. Murphy House |
| Smith, Hiram C., House |
| Smith, Hiram C., Milking Shed |
| Smith, James, House |
| Smith, James J. and Anna J. (Linean), House #1 |
| Smith, James J. and Anna J. (Linean), House #2 |
| Smith, John, House |
| Smith-Johnson House |
| Smith, Peter and Mary, House |
| Smith, William G., House |
Data from United States Park Service and Wikidata
