Indiana - Significance region: National
| Ade, George, House |
| Allen County Courthouse |
| Allison Mansion |
| Angel Mounds |
| Archeological Sites 12T59 and 12T530 |
| Auburn Cord Duesenberg Automobile Facility |
| "B-17G ""Flying Fortress"" No. 44-83690" |
| Bailly, Joseph, Homestead |
| Bates-Hendricks House |
| Beardsley, Albert R., House |
| Beeson Bridge |
| Bentel, George, House |
| Big Rocky Fork Bridge |
| Billie Creek Bridge |
| Birdsall, Mary, House |
| Bowsher Ford Bridge |
| Bridgeton Bridge |
| Broad Ripple Park Carousel |
| Brookville Historic District |
| Butler Fieldhouse |
| Cannelton Cotton Mills |
| Catlin Bridge |
| Centerville Historic District |
| Chesapeake & Ohio 2-8-4 Steam Engine No. 2789 |
| Chief Richardville House and Miami Treaty Grounds |
| Christian, John E. and Catherine E., House (Samara) |
| Chrysler Enclosure |
| Coffin, Levi, House |
| Conley's Ford Bridge |
| Corydon Historic District |
| Cowles Bog |
| Cox Ford Bridge |
| Crooks Bridge |
| Crown Hill Cemetery |
| Crown Hill National Cemetery |
| Debs, Eugene V., House |
| de Richardville, Chief Jean-Baptiste, House |
| Duck Creek Aqueduct |
| Evansville Post Office |
| First Christian Church |
| Fort Benjamin Harrison Historic District |
| Fort Wayne Park and Boulevard System Historic District |
| Fort Wayne Performing Arts Theatre |
| George Rogers Clark National Historical Park |
| Good Fellow Club Youth Camp |
| Hamilton County Courthouse Square |
| Harrison, Benjamin, House |
| Harrison, William Henry, Home (Grouseland) |
| Harry Evans Bridge |
| Hay-Morrison House |
| Hillforest (Forest Hill) |
| Indianapolis Motor Speedway |
| Indianapolis Park and Boulevard System |
| Indianapolis Union Railroad Station |
| Indiana State Capitol |
| Indiana State Prison South-Indiana Reformatory- Colgate-Palmolive Historic District |
| Indiana Theatre |
| Indiana War Memorial Historic District |
| Jackson Bridge |
| Jacobs, Terrell, Circus Winter Quarters |
| Jeffries Ford Bridge |
| Jennison Guard Site |
| Johnny Appleseed Memorial Park |
| Lanier Mansion |
| Leatherwood Station Bridge |
| Lilly Biological Laboratories |
| Lincoln Boyhood National Memorial |
| Lockerbie Square Historic District |
| Lockheed PV-2 Harpoon No. 37396 |
| Lusk Home and Mill Site |
| Madison Historic District |
| Mann Site |
| Mansfield Bridge |
| Marshall Bridge |
| McAllister Bridge |
| Mecca Bridge |
| Melcher Bridge |
| Merom Site and Fort Azatlan |
| Mill Creek Bridge |
| Morton, Oliver P., House |
| Mounds State Park |
| Murphy Archeological Site |
| Narrows Bridge |
| Neet Bridge |
| Nevins Bridge |
| New Albany National Cemetery |
| New Castle Archeological Site |
| New Harmony Historic District |
| Ninde-Mead-Farnsworth House |
| Old Cathedral Complex |
| Old Clarksville Site |
| Oldfields |
| Old Pathology Building |
| Orange County Courthouse |
| Osborn Site |
| Phillips Bridge |
| Porter, Gene Stratton, Cabin |
| Porter, Gene Stratton, Cabin |
| Portland Mills Bridge |
| Prairie Creek Site |
Data from United States Park Service and Wikidata
