Illinois - Significance region: National
| Abbott, Robert S., House |
| Adler Planetarium |
| Albany Mounds Site |
| Allerton, Robert, Estate |
| Alta Vista Terrace Historic District |
| Altgeld Gardens–Philip Murray Homes Historic District |
| Altgeld Hall, University of Illinois |
| Alton Military Prison Site |
| Alton National Cemetery |
| Armour Square |
| Auditorium Building, Roosevelt University |
| Aurora College Complex |
| Automatic Electric Company Building |
| AVR 661 |
| Bach, Emil, House |
| Baker, Frank J., House |
| Balaban and Katz Chicago Theatre |
| Bane, Warren, Site |
| Barber, Henry D., House |
| Batavia Institute |
| Battery Rock |
| Beecher Hall, Illinois College |
| Benjamin, Ruben M., House |
| Bishop Hill Historic District |
| Bohemian National Cemetery |
| Bowen, Joseph T., Country Club |
| Boyce Building |
| Brandon Road Lock and Dam Historic District |
| Bryan, William Jennings, Boyhood Home |
| Building at 1401-1407 Elmwood Avenue |
| Buildings at 860-880 Lake Shore Drive |
| Cahokia Mounds |
| Cairo Historic District |
| Campana Factory |
| Camp Butler National Cemetery |
| Carson, Pirie, Scott and Company |
| Carter, Frederick B., Jr., House |
| Carthage Jail |
| Central Park Theater |
| Chain of Rocks Bridge |
| Chanute Field Historic District |
| Chapin and Gore Building |
| Charnley, James, House |
| Charter Oak Schoolhouse |
| Chicago Board of Trade Building |
| Chicago, Burlington, & Quincy Roundhouse and Locomotive Shop |
| Chicago Federal Center |
| Chicago Golf Club |
| Chicago Park Boulevard System Historic District |
| Chicago Portage National Historic Site |
| Church of the Holy Family |
| Clarke, Henry B., House |
| Clayville Tavern |
| Clear Lake Site |
| Cleiman Mound and Village Site |
| Clover Lawn |
| Cluever, Richard, House |
| Columbus Park |
| Columbus Park |
| Compton, Arthur H., House |
| Cook County Hospital Administration Building |
| Coonley, Avery, House |
| Coonley, Avery, School |
| Creole House |
| Crow Island School |
| Curtiss-Wright Hangars 1 and 2 |
| Dana, Susan Lawrence, House |
| Davis Square |
| Dawes, Charles Gates, House |
| Deere, John, House and Shop |
| Delaware Building |
| Denkmann-Hauberg House |
| De Priest, Oscar Stanton, House |
| Dickson Mounds |
| Dogtooth Bend Mounds and Village Site |
| Douglas Tomb State Memorial |
| Dresden Island Lock and Dam Historic District |
| Drummond, William E., House |
| Dryden, George B., House |
| Duffy Site |
| Duncan Farm |
| Duncan, Joseph, House |
| Du Sable, Jean Baptiste Point, Homesite |
| Ellwood Mansion |
| Elsah Historic District |
| Emerald Mound and Village Site |
| Fabyan Villa |
| Fairbanks, Morse and Company Building |
| Farm Creek Section |
| Farnsworth House |
| Field Museum of Natural History |
| First Congregational Church of Austin |
| First Self-Sustaining Nuclear Reaction, Site of |
| Fisher Building |
| Ford Airport Hanger |
| Ford, Sam and Ruth Van Sickle, House |
| Fort de Chartres |
| Fort Massac Site |
| Fort Sheridan Historic District |
| Frank Lloyd Wright-Prairie School of Architecture Historic District |
Data from United States Park Service and Wikidata
