Florida - Significance region: Local
| Dade City Atlantic Coast Line Railroad Depot |
| Dade City Woman's Club |
| Dade County Courthouse |
| Davenport Historic District |
| Davie School |
| Davie Woman's Club |
| Davis, W.T., Building |
| Daytona Beach Bandshell and Oceanfront Park Complex |
| Daytona Beach Surfside Historic District |
| Dean Park Historic Residential District |
| DeCanizares, F.A., House |
| Deerfield School |
| Deerfield School |
| Deering, Charles, Estate |
| DeLand Memorial Hospital, Old |
| DeLeon Springs Colored School |
| Delray Beach Schools |
| DeMarcay Hotel |
| Denham-Lacy House |
| Dennis-Coxetter House |
| Dennis Hotel |
| Desert Inn |
| Devil's Millhopper |
| Dezell House |
| Dial-Goza House |
| Dickinson Memorial Library and Park |
| Dickman, A.P., House |
| Dillard High School, Old |
| Dix House |
| Dixie Crystal Theatre |
| Dixie Highway-Hastings, Espanola and Bunnell Road |
| Dixieland Historic District |
| Dixie Walesbilt Hotel |
| Domestic Science and Manual Training School |
| Don Ce Sar Hotel |
| Donnelly, Bartholomew J., House |
| Dorr, Clara Barkley, House |
| Dorsey, D. A., House |
| Douglas, J. O., House |
| Downtown Boca Grande Historic District |
| Downtown Bonifay Historic District |
| Downtown Carrabelle Historic District |
| Downtown DeLand Historic District |
| Downtown Haines City Commercial District |
| Downtown Jacksonville Historic District |
| Downtown LaBelle Historic District |
| Downtown Miami Historic District |
| Downtown Plant City Commercial District |
| Downtown Plant City Historic Residential District |
| Downtown Sarasota Historic District |
| Downtown St. Petersburg Historic District |
| Downtown Wauchula Historic District |
| Downtown Winter Haven Historic District |
| Downtown Winter Park Historic District |
| Driftwood Inn and Restaurant |
| Duette School |
| Duff, Capt. F. Deane, House |
| Dunbar, Paul Lawrence, School |
| Duncan, Harry C., House |
| Duncan, Horace, House |
| Dundee ACL Railroad Depot, Old |
| Dunedin Isles Golf Club Golf Course |
| Dunlawton Avenue Historic District |
| Dunnellon Boomtown Historic District |
| DuPont, Alfred I., Building |
| Durkee Gardens Historic District |
| Durkee, Joseph H., Athletic Field |
| Duval County Armory |
| Earle House |
| East Lake Morton Residential District |
| Eastside Historic District |
| Eastwood Terrace Hotel |
| Eden Mansion |
| Edge House |
| Edgewood Historic District |
| Edison Park Elementary School |
| Edison, Thomas, Winter Estate |
| Edmunds, John, Apartment House |
| Edwards Theatre |
| Edward Waters College Historic District |
| El Centro Espanol of West Tampa |
| El Cid Historic District |
| El Jobean Hotel |
| El Jobean Post Office and General Store |
| Elks Club Building |
| El Pasaje |
| El Patio Apartments |
| El Pino Parque Historic District |
| El Real Retiro |
| El Vernona Apartments-Broadway Apartments |
| El Vernona Hotel-John Ringling Hotel |
| English, J. Colin, School |
| Entrance to Central Miami |
| Episcopal House of Prayer |
| Epworth Hall |
| Ervin's Rest |
| Espanola Schoolhouse |
| Estes, R.W. Celery Company Precooler Historic District |
| Etheredge House |
| Eustis Commercial Historic District |
Data from United States Park Service and Wikidata
