Delaware - Area of significance: Industry
| Abbott's Mill |
| American Vulcanized Fibre Company-Wilmington Plant |
| Auburn Mills Historic District |
| Augustine Paper Mill |
| Baltimore Mills Historic Archaeological Site |
| Bancroft and Sons Cotton Mills |
| Beard, Duncan, Site |
| Bethel Historic District |
| Bonwell House |
| Brandywine Manufacturers Sunday School |
| Brandywine Powder Mills District |
| Brandywine Village Historic District |
| Brecknock |
| Breck's Mill Area |
| Brindley Farm |
| Chipman's Mill |
| Cooch's Bridge Historic District |
| Dean, Joseph, & Son Woolen Mill |
| Deep Creek Furnace Site |
| Duck Creek Village |
| East Brandywine Historic District |
| Eastburn-Jeanes Lime Kilns Historic District |
| Eleutherian Mills |
| Fisher, Andrew, House |
| Garrett Snuff Mill |
| Garrett Snuff Mills Historic District |
| Georgetown Coal Gasification Plant |
| Graves Mill Historic District |
| Greenbank Historic Area |
| Hale-Byrnes House |
| Harlan and Hollingsworth Office Building |
| Hearn and Rawlins Mill |
| Ivy Dale Farm |
| Lewes Historic District |
| Lobdell Estate, Minquadale Home |
| Lower Louviers and Chicken Alley |
| Main Office of the New Castle Leather Company |
| Meteer Store House |
| Mount Cuba Historic District |
| New Castle Leather Raw Stock Warehouse |
| Noxontown |
| Pine Grove Furnace Site |
| Reading, Philip, Tannery |
| Robinson House |
| Rockland Historic District |
| Tatnall, Joseph, House |
| Townsend Historic District |
| Victorian Dover Historic District |
| Walker's Mill and Walker's Bank |
| Warren's Mill |
| Wilkerson, J. H., & Son Brickworks |
| Wilmington Club |
| Wooddale Historic District |
| Woodward Houses |
Data from United States Park Service and Wikidata