All - Constructed - 1920–1929
| Second Street-Gun River Bridge |
| Seven Dolors Catholic Church |
| Seventy-First Consolidated School |
| Shackford Hall |
| Shadowcliff |
| Shady Rest Golf and Country Club |
| Shafer Barn |
| Shaffer, Henry K. and Mary E., House |
| Shaffer, John C., Barn |
| Shakamak State Park Historic District |
| Shamrock Mills |
| Shawnee High School |
| Shay, Lee, Farmhouse |
| Shea's Buffalo Theater |
| Sheboygan Theater |
| Sheffield Apartments |
| Shelbridge |
| Shelby Consolidated School |
| Shelby Town Hall |
| Shell Building, The |
| Sherburne Ranger Station Historic District |
| Sheridan Square Apartments |
| Sherman Building |
| Sherman Line Rosenwald School |
| Shoreline Apartments |
| Shrine of the Black Madonna of the Pan African Orthodox Christian Church |
| Sigma Pi Fraternity House |
| Sikes, John C., House |
| Simmons & Wright Company, The |
| Simpson's, Billy, House of Seafood and Steaks |
| Sims High School |
| Sinclair Service Station |
| Singer Sewing Company |
| Sioux City Public Library (Smith Villa Branch) |
| Sixteenth Street Bridge |
| Skyline Lodge |
| Slocum House |
| Smathers, Frank, House |
| Smith, A. C., & Co. Gas Station |
| Smith, Dr. E. Sanborn, House |
| Smith Jr., Isaac H., House |
| Smith, Lloyd R., House |
| Snake River Ranch |
| Snow Creek Ski Hut |
| Snyder, H. E., House |
| Soden's Grove Bridge |
| Soldani Mansion |
| Soldiers and Sailors Memorial Building |
| Somoresworth High School |
| Soulsby Service Station |
| Southerland-Burnette House |
| Southern Bell Telephone Company Building |
| Southern Bleachery and Print Works |
| Southern Railway Building |
| Southern Railway Freight Station |
| South Junior High School |
| South Side Masonic Lodge No. 1114 |
| South Side National Bank |
| South Side School |
| South Superior Union Hall |
| South Water Market |
| Southwestern Bell Telephone Building |
| Southworth House |
| Sovereign Hotel |
| Sparta Masonic Temple |
| Sperling, George, House and Outbuildings |
| Spies-Robinson House |
| Spillman Engineering 3-Abreast Carousel |
| Spink County Courthouse |
| Sprague Branch of the Salt Lake City Public Library |
| Spring Garden School No. 1 |
| Spruce Lodge |
| Spruce Street YMCA |
| Sprucewold Lodge |
| Spur Gasoline Station |
| Squaw Peak Inn |
| St. Alphonsus' Hospital Nurses' Home and Heating Plant/Laundry |
| Stambaugh, Henry H., Memorial Auditorium |
| Standard Drug Company |
| Standard Drug No. 2 |
| Standard Oil Company Headquarters |
| St. Andrews Patrol Cabin |
| Stanley Theater and Clark Building |
| St. Anthony School |
| Stanton, Edwin M., School |
| Starkweather School |
| State Office Building |
| State Soldiers Home Barn |
| State Steet Bridge |
| State Theater |
| State Theatre |
| Station 13 Minneapolis Fire Department |
| St. Boniface Roman Catholic Church |
| St. Charles Apartments |
| St. Charles Bridge |
| St. Columba School |
| St. Dominic's Church |
| Steedman Estate |
| Steere, A. C., Elementary School |
| Stellafane Observatory |
Data from United States Park Service and Wikidata
