All - Constructed - 1890–1899
| Schrage, Henry and Caroline, House |
| Schuerenberg, F. W., House |
| Schuster, George, House and Carriage Shed |
| Scofield-Sanor House |
| Scranton Lace Company |
| Sears, Jacob, Memorial Library |
| Second Brazer Building |
| Second Yadkin County Jail |
| Security Building |
| Seiter, Joseph, House |
| Sequoia Union High School |
| Seth Richards Commercial Block |
| Seul Choix Pointe Light Station |
| Seven Oaks |
| Seymour, Edward B., House |
| Shallcross |
| Sherburne, Warren E., House |
| Sherman County Courthouse |
| Shiloh Baptist Church (Old Site) |
| Shiloh National Military Park |
| Shimek, Bohumil, House |
| Shivelbine, August and Amalia, House |
| Shook-Vanzant Farm |
| Shoop Building |
| Shoreby Hill Historic District |
| Shubuta Baptist Church |
| Shubuta Methodist Episcopal Church, South |
| Shute-Meierjurgen Farmstead |
| Sibley and Holmwood Candy Factory and Witkop and Holmes Headquarters |
| Silverman, Morris, House |
| Simmons, John P., House |
| Simpson House |
| Simpson Memorial United Methodist Church |
| Skagway Historic District and White Pass |
| Smith, Charles R., House |
| Smith-Elisha House |
| Smith, Ellen, House |
| Smith, Fleming, Warehouse |
| Smith, George W., House |
| Smith, Henry Spencer, House |
| Smith-Marcuse-Lowry House |
| Smith, Milo A., House |
| Smith Point Light Station |
| Smith's Grain and Feed Store |
| Smith, W. F., and Sons Leaf House and Brown Brothers Company Building |
| Smithwick's Creek Primitive Baptist Church |
| Smith, William R., House |
| Smoky Valley Roller Mill |
| Snead Junior College Historic District |
| Snook House |
| Snoqualmie Falls Hydroelectric Power Plant Historic District |
| Snow Hill Covered Bridge |
| Snow, Lemuel, Jr., House |
| Society for Savings Building |
| Somervell County Courthouse |
| Somerville Journal Building |
| Sommer, Morris, House |
| Sonoma State Home-Main Building |
| South Bass Island Light |
| South Broad-East Fifth Streets Historic District |
| Southern Railway Passenger Station |
| South Georgia College Administration Building |
| South Hall, River Falls State Normal School |
| South High School |
| South Station Headhouse |
| Spalding Memorial Library-Tioga Point Museum |
| Spitzer Building |
| Splitlog Church |
| Spooner Hall, University of Kansas |
| Spring City School |
| Spring Point Ledge Light Station |
| Spurgin Residence |
| Squirrel Point Light Station |
| Stackpole, Moore, and Tryon Building |
| Stafford's Wells Hotel |
| Standrod House |
| St. Anthony de Padua Parish School |
| St. Anthony Pegram Truss Railroad Bridge |
| Stark Building |
| Stark, Robert M., House |
| State Bridge |
| St. Augustine Alligator Farm Historic District |
| Stay House |
| St.Bonifacius Kirche Complex |
| St. Catherine's School |
| St. Clair River Tunnel |
| Steamboat House |
| Stebbins, Edward N. and Mary T., House |
| Steensland, Halle, House |
| Stegmaier Brewery |
| Steinbeck, John, House |
| Steiner Bank Building |
| St. Elizabeth Hospital (Old) |
| St. Elizabeth's Convent |
| St. Elizabeth's Retreat Chapel |
| Stevens, Ann, House |
| Stevenson House |
| Stewart, Frank, House |
| Stewart Home School |
| Stewart Indian School |
Data from United States Park Service and Wikidata
