All - Constructed - 1850–1859
| Shady Brook Farm |
| Shaft, William C. & Jane, House |
| Shaw-Hammons House |
| Shoemake, John H., House |
| Shoe Shop-Doucette Ten Footer |
| Shopiere Congregational Church |
| Silliman Institute |
| Sisters of St. Dominic Motherhouse Complex |
| Site No. RH00-062 |
| Skumsrud, Nils, House |
| Sledge-Hayley House |
| Sleepy Hollow Cemetery |
| Sloan, Samuel, House |
| Smallpox Hospital |
| Smith, Adon, House |
| Smith, Alvin T., House |
| Smith-Buntura-Evans House |
| Smith, Daniel, House |
| Smith, Henry H./J.H. Murphy House |
| Smith, Henry W., House |
| Smith, Hiram, House |
| Smith House |
| Smith Island Light Station |
| Smith, James J. and Anna J. (Linean), House #1 |
| Smith-Johnson House |
| Smith-Joseph-Stratton House |
| Smith, Warner Price Mumford, House |
| Snugs, Isaiah Wilson, House, and Marks House |
| Snyder, Noah, Farm |
| Sodality Chapel |
| Somerville High School |
| South Bushwick Reformed Protestant Dutch Church Complex |
| South Congregational Church |
| South River Presbyterian Church |
| South School |
| South Trade Street Houses |
| Southwest District School |
| Sparks-Anderson House |
| Spirit Lake Massacre Log Cabin |
| Spooner-Haight Farmstead |
| Squirewood Hall |
| Stagg House |
| St. Aloysius Catholic Church |
| St. Alphonsus Church |
| Stanley, Leonard W., House |
| Stannard House |
| Stanton Hall |
| State Bank of Wisconsin |
| Stauber, Samuel B., Farm |
| St. Augustine Catholic Church |
| St. Augustine Catholic Church and Cemetery |
| St. Augustine's Catholic Church |
| St. Clement's Protestant Episcopal Church |
| Stedman, Sarah Lowe, House |
| Steilacoom Catholic Church |
| Steinway House |
| St. Elizabeths Hospital |
| Stevens, Andrew J., House |
| Stevens, Everitt P., House |
| St. George's Church |
| St. George's Episcopal Church |
| St. Helena Public Cemetery |
| St. Ignatius Mission |
| St. James Catholic Church and Cemetery |
| St. John Chrysostom Church |
| St. John's Catholic Church |
| St. John's Episcopal Church |
| St. John's Episcopal Church |
| St. John the Baptist Catholic Church |
| St. John the Baptist Roman Catholic Church |
| St. John the Evangelist Roman Catholic Church |
| St. Joseph Roman Catholic Church |
| St. Louis Catholic Church |
| St. Louis Plantation |
| St. Luke's Hospital |
| St. Mark's Episcopal Church |
| St. Mary's Cathedral and Rectory |
| St. Mary's Chapel |
| St. Mary's Falls Canal |
| St. Mary's Roman Catholic Church Complex |
| St. Matthias Episcopal Church |
| Stone Barn Farm |
| Stoner, Joseph J., House |
| Stone's Bridge |
| Stony Hill School |
| Stoughton Universalist Church |
| Stowe, Harriet Beecher, House |
| St. Patrick's Cathedral |
| St. Patrick's Church |
| St. Patrick's Church-Garryowen |
| St. Patrick's Roman Catholic Church, Rectory, and School |
| St. Paul's Episcopal Church |
| St. Peters Church and Buildings |
| St. Peter's Roman Catholic Church-St. Mary's School |
| St. Peters United Evangelical Lutheran Church |
| St. Raymond's Church |
| St. Rose Roman Catholic Church Complex |
| Strunk-Nyssen House |
| St. Thomas' Episcopal Church |
| Sturdivant Hall |
Data from United States Park Service and Wikidata
