All - Architectural style - Federal architecture
| Seaside Plantation House |
| Second Baptist Church of Dover |
| Second Church of Christ |
| Second Old School Baptist Church of Roxbury |
| Seeley, Samuel W., House |
| See-Ward House |
| Sells, Eliud, House |
| Selma Plantation House |
| Selwyn |
| Semmes, Raphael, House |
| Seven Hearths |
| Seventh Day Baptist Church |
| Sewall-Scripture House |
| Shadow Lawn |
| Shady Grove |
| Shady Oaks |
| Shafer's Mill |
| Shaker West Lot Farm |
| Sharp, Edward, House |
| Sharp, Elisha, House |
| Sharples Homestead |
| Sharpless Homestead |
| Shawhan, Joseph, House |
| Shawnee Mission |
| Shear, Israel, House |
| Sheldon Cobblestone House |
| Sherman Farm |
| Sherman House |
| Shew, Godfrey, House |
| Shields, David, House |
| Ship Inn |
| Shirley, James, House |
| Shirts, William, House |
| Shobe-Morrison House |
| Shoemake, John H., House |
| Sibley, Hiram, Homestead |
| Siler, Jesse R., House |
| Simmons-Edwards House |
| Simonds Tavern |
| Simons' Inn |
| Simpson, Dr. Thomas, House |
| Simpson's Grove |
| Sion Hill |
| Skeele, Capt. J. S., House |
| Sleepy Hollow Farm |
| Sleepy Hollow Hall |
| Sliker Cobblestone House |
| Smallwood, Eli, House |
| Smith, Abigail Adams, Museum |
| Smith, Benjamin, House |
| Smith-Davis House |
| Smith, Enoch, House |
| Smithfield Exchange Bank |
| Smithfield Farm |
| Smith, Gerrit, Estate |
| Smith, Hannah Maria Libby, House |
| Smith, Henry Tunis, Farm |
| Smith, James, Tanyard |
| Smith-Jessup House |
| Smithland |
| Smith-Little-Mars House |
| Smith, Obadiah, House |
| Smith, Simeon, House |
| Smith, Simeon P., House |
| Smith, Thomas, House |
| Smith, William, House |
| Snook, Van B., House |
| Snow Hill |
| Snow, John, House |
| Soldier's Rest |
| Solitude Plantation House |
| Somerset |
| Somerville Courthouse |
| South Canaan Congregational Church |
| South Carolina Governor's Mansion |
| South Congregational Church |
| Southgate Farm |
| South Reading Academy |
| South Salem Academy |
| South Tunbridge Methodist Episcopal Church |
| South Union Shaker Center House and Preservatory |
| Southwick, Elisha, House |
| Southworth House |
| Spalding Hall, St. Joseph's College |
| Spangenberg, Frederick, House |
| Sparrow, James, House |
| Speck, Peter, House |
| Spencer-Pierce-Little House |
| Spicer-Millard House |
| Spite House |
| Sprague, David, House |
| Sprague House |
| Sprague House |
| Sprague, Jonathan, House |
| Springdale |
| Springdale |
| Springdale |
| Springdale Farm |
| Springer, Charles, Tavern |
| Springfield |
Data from United States Park Service and Wikidata
